After working as a creative associate at NBC, Henderson realized she wanted to become a writer, and soon became an apprentice on the sitcom Family Matters, and on The Fresh Prince of Bel Air two years later. She co-produced Moesha and Sister, Sister, and developed the TV series Soul Food for television.[2] It became the longest running drama in television history to star a black cast, and earned several NAACP Image Awards.[1]She graduated from the University of California, Los Angeles in 2004 with a Master of Fine Arts degree. She and three of her friends, Mara Brock Akil, Gina Prince-Bythewood, and Sara Finney-Johnson endowed the Four Sisters Scholarship in Screenwriting, Directing, and Animation to support students interested in projects depicting the African American experience.[1][3] She is currently a PhD candidate in the school's Cinema and Media Studies program.[1]Henderson worked as a co-executive producer for the teen drama series Gossip Girl.[1] She also served as a co-executive producer on the first season of the science-fiction television series Fringe, before leaving to begin as a writer on the DC Comics series Teen Titans, Static Shock, as well as other projects.[4]Her recent television drama credits include "Marvel's The Punisher" and "The Quad."